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Target
Transitional endoplasmic reticulum ATPase
Ligand
BDBM46579
Substrate
n/a
Meas. Tech.
Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase
IC50
>50000±n/a nM
Citation
 PubChem, PC Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase PubChem Bioassay (2009)[AID] 
Target
Name:
Transitional endoplasmic reticulum ATPase
Synonyms:
TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein
Type:
Enzyme
Mol. Mass.:
89300.63
Organism:
Homo sapiens (Human)
Description:
P55072
Residue:
806
Sequence:
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG
  
Inhibitor
Name:
BDBM46579
Synonyms:
2-chloranyl-1-[(5E)-5-[[2-(2-chlorophenyl)hydrazinyl]methylidene]pyrrol-3-yl]ethanone | 2-chloro-1-[(5E)-5-[[(2-chlorophenyl)hydrazo]methylidene]-3-pyrrolyl]ethanone | 2-chloro-1-[(5E)-5-[[2-(2-chlorophenyl)hydrazinyl]methylidene]pyrrol-3-yl]ethanone | 2-chloro-1-[(5E)-5-[[N'-(2-chlorophenyl)hydrazino]methylene]pyrrol-3-yl]ethanone | 4-(2-chloroacetyl)-1H-pyrrole-2-carbaldehyde N-(2-chlorophenyl)hydrazone | MLS000763473 | SMR000336813 | cid_5930716
Type:
Small organic molecule
Emp. Form.:
C13H11Cl2N3O
Mol. Mass.:
296.152
SMILES:
ClCC(=O)c1c[nH]c(CN=Nc2ccccc2Cl)c1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: