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Target
Mucolipin-3
Ligand
BDBM46898
Substrate
n/a
Meas. Tech.
Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)
EC50
5500±n/a nM
Citation
 PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay (2009)[AID] 
Target
Name:
Mucolipin-3
Synonyms:
MCLN3_HUMAN | MCOLN3 | MCOLN3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64244.09
Organism:
Homo sapiens (Human)
Description:
Q8TDD5
Residue:
553
Sequence:
MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK
  
Inhibitor
Name:
BDBM46898
Synonyms:
1-(3-Benzoyl-thioureido)-3,3-dimethyl-3,4-dihydro-naphthalene-2-carboxylic acid ethyl ester | 1-(benzoylthiocarbamoylamino)-3,3-dimethyl-4H-naphthalene-2-carboxylic acid ethyl ester | 1-[[benzamido(sulfanylidene)methyl]amino]-3,3-dimethyl-4H-naphthalene-2-carboxylic acid ethyl ester | MLS000552334 | SMR000174058 | cid_1115489 | ethyl 1-(benzoylcarbamothioylamino)-3,3-dimethyl-4H-naphthalene-2-carboxylate | ethyl 3,3-dimethyl-1-(phenylcarbonylcarbamothioylamino)-4H-naphthalene-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C23H24N2O3S
Mol. Mass.:
408.513
SMILES:
CCOC(=O)C1=C(NC(=S)NC(=O)c2ccccc2)c2ccccc2CC1(C)C |c:5|
Structure:
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