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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | MCOLN3 protein | ||
| Ligand | BDBM46993 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) | ||
| EC50 | 819±n/a nM | ||
| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| MCOLN3 protein | |||
| Name: | MCOLN3 protein | ||
| Synonyms: | n/a | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 64244.09 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q8TDD5 | ||
| Residue: | 553 | ||
| Sequence: |
| ||
| BDBM46993 | |||
| Name | BDBM46993 | ||
| Synonyms: | 5-methyl-3-phenyl-4-(2-tosylpyrazol-3-yl)isoxazole | 5-methyl-4-[2-(4-methylphenyl)sulfonyl-3-pyrazolyl]-3-phenylisoxazole | 5-methyl-4-[2-(4-methylphenyl)sulfonylpyrazol-3-yl]-3-phenyl-1,2-oxazole | 5-methyl-4-{1-[(4-methylphenyl)sulfonyl]-1H-pyrazol-5-yl}-3-phenylisoxazole | MLS001111124 | SMR000457058 | cid_2745600 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H17N3O3S | ||
| Mol. Mass. | 379.432 | ||
| SMILES | Cc1onc(c1-c1ccnn1S(=O)(=O)c1ccc(C)cc1)-c1ccccc1 |(6.9,-1.41,;7.81,-.16,;9.35,-.16,;9.82,1.3,;8.58,2.21,;7.33,1.3,;5.87,1.78,;5.39,3.24,;3.85,3.24,;3.37,1.78,;4.62,.87,;4.62,-.67,;6.16,-.67,;3.08,-.67,;4.62,-2.21,;3.29,-2.98,;3.29,-4.52,;4.62,-5.29,;4.62,-6.83,;5.95,-4.52,;5.95,-2.98,;8.58,3.75,;9.91,4.52,;9.91,6.06,;8.58,6.83,;7.24,6.06,;7.24,4.52,)| | ||
| Structure |  | ||
| n/a | |||