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Target
Procathepsin L
Ligand
BDBM33517
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
205.113333±61.964382 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM33517
Synonyms:
2-[[5-[(1S)-1-amino-2-phenyl-ethyl]-1,3,4-oxadiazol-2-yl]thio]-N,N-dimethyl-acetamide;hydrochloride | 2-[[5-[(1S)-1-amino-2-phenylethyl]-1,3,4-oxadiazol-2-yl]sulfanyl]-N,N-dimethylacetamide;hydrochloride | 2-[[5-[(1S)-1-amino-2-phenylethyl]-1,3,4-oxadiazol-2-yl]thio]-N,N-dimethylacetamide;hydrochloride | 2-[[5-[(1S)-1-azanyl-2-phenyl-ethyl]-1,3,4-oxadiazol-2-yl]sulfanyl]-N,N-dimethyl-ethanamide;hydrochloride | MLS000042386 | SMR000043830 | cid_6602827
Type:
Small organic molecule
Emp. Form.:
C14H18N4O2S
Mol. Mass.:
306.383
SMILES:
CN(C)C(=O)CSc1nnc(o1)[C@@H](N)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: