Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM42702
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM42702
Synonyms:
5-(3-Bromo-phenyl)-3H-[1,3,4]oxadiazole-2-thione | 5-(3-bromophenyl)-3H-1,3,4-oxadiazole-2-thione | MLS000085023 | SMR000019369 | cid_794839
Type:
Small organic molecule
Emp. Form.:
C8H5BrN2OS
Mol. Mass.:
257.107
SMILES:
Sc1nnc(o1)-c1cccc(Br)c1
Structure:
Search PDB for entries with ligand similarity: