Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46597
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46597
Synonyms:
(2,4-dimethylphenyl)-(6-methyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-yl)amine | MLS-0246735.0001 | N-(2,4-dimethylphenyl)-6-methyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-amine | cid_5293705
Type:
Small organic molecule
Emp. Form.:
C13H16N4S
Mol. Mass.:
260.358
SMILES:
Cc1cc2NC(Nc3ccc(C)cc3C)Sn2n1
Structure:
Search PDB for entries with ligand similarity: