Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46629
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46629
Synonyms:
2-[2-chloranyl-5-(trifluoromethyl)phenyl]-6-nitro-1,2-benzothiazol-3-one | 2-[2-chloro-5-(trifluoromethyl)phenyl]-6-nitro-1,2-benzothiazol-3-one | MLS-0315781.0001 | cid_1518797
Type:
Small organic molecule
Emp. Form.:
C14H6ClF3N2O3S
Mol. Mass.:
374.722
SMILES:
[O-][N+](=O)c1ccc2c(c1)sn(-c1cc(ccc1Cl)C(F)(F)F)c2=O
Structure:
Search PDB for entries with ligand similarity: