Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46633
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46633
Synonyms:
2-(3-nitrophenyl)naphtho[2,3-g][1,2]benzothiazole-3,6,11-trione | MLS-0315785.0001 | cid_4317404
Type:
Small organic molecule
Emp. Form.:
C21H10N2O5S
Mol. Mass.:
402.38
SMILES:
[O-][N+](=O)c1cccc(c1)-n1sc2c3C(=O)c4ccccc4C(=O)c3ccc2c1=O
Structure:
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