Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46640
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46640
Synonyms:
2-phenylnaphtho[2,3-g][1,2]benzothiazole-3,6,11-trione | MLS-0315791.0001 | cid_4695672
Type:
Small organic molecule
Emp. Form.:
C21H11NO3S
Mol. Mass.:
357.382
SMILES:
O=C1c2ccccc2C(=O)c2c1ccc1c2sn(-c2ccccc2)c1=O
Structure:
Search PDB for entries with ligand similarity: