Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46649
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46649
Synonyms:
MLS-0315798.0001 | N,N-diethyl-4-(3-keto-1,2-benzothiazol-2-yl)benzenesulfonamide | N,N-diethyl-4-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzenesulfonamide | N,N-diethyl-4-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide | cid_2327952
Type:
Small organic molecule
Emp. Form.:
C17H18N2O3S2
Mol. Mass.:
362.466
SMILES:
CCN(CC)S(=O)(=O)c1ccc(cc1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: