Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46676
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46676
Synonyms:
(Z)-(4-chlorodithiazol-5-ylidene)-(1,3,4-thiadiazol-2-yl)amine | (Z)-4-chloranyl-N-(1,3,4-thiadiazol-2-yl)-1,2,3-dithiazol-5-imine | (Z)-4-chloro-N-(1,3,4-thiadiazol-2-yl)-5-dithiazolimine | (Z)-4-chloro-N-(1,3,4-thiadiazol-2-yl)dithiazol-5-imine | MLS-0390818.0001 | cid_6114286
Type:
Small organic molecule
Emp. Form.:
C4HClN4S3
Mol. Mass.:
236.726
SMILES:
Clc1nss\c1=N/c1nncs1
Structure:
Search PDB for entries with ligand similarity: