Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46715
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46715
Synonyms:
(4-chlorodithiazol-5-ylidene)-(6-quinolyl)amine | 4-chloranyl-N-quinolin-6-yl-1,2,3-dithiazol-5-imine | 4-chloro-N-(6-quinolinyl)-5-dithiazolimine | 4-chloro-N-quinolin-6-yldithiazol-5-imine | MLS-0390905.0001 | cid_483864
Type:
Small organic molecule
Emp. Form.:
C11H6ClN3S2
Mol. Mass.:
279.768
SMILES:
Clc1nss\c1=N\c1ccc2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: