Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM46057
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
792±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM46057
Synonyms:
5-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 5-fluoro-2-phenyl-1,2-benzothiazol-3-one | ML089 | MLS-0315921.0001 | cid_22416235
Type:
Small organic molecule
Emp. Form.:
C13H8FNOS
Mol. Mass.:
245.272
SMILES:
Fc1ccc2sn(-c3ccccc3)c(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: