Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47645
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
339.7±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47645
Synonyms:
(2E)-1-phenyl-3-[4-(3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)phenyl]prop-2-en-1-one | (E)-1-phenyl-3-[4-(3-phenyl-2-pyrazolin-1-yl)phenyl]prop-2-en-1-one | (E)-1-phenyl-3-[4-(5-phenyl-3,4-dihydropyrazol-2-yl)phenyl]-2-propen-1-one | (E)-1-phenyl-3-[4-(5-phenyl-3,4-dihydropyrazol-2-yl)phenyl]prop-2-en-1-one | MLS000720174 | SMR000304703 | cid_16193971
Type:
Small organic molecule
Emp. Form.:
C24H20N2O
Mol. Mass.:
352.4284
SMILES:
O=C(C=Cc1ccc(cc1)N1CCC(=N1)c1ccccc1)c1ccccc1 |w:3.3,c:14|
Structure:
Search PDB for entries with ligand similarity: