Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47658
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
2073±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47658
Synonyms:
1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl)urea | 1-(4-methylphenyl)-3-[2-(3-pyridinyl)-4-pyrimidinyl]urea | 1-(p-tolyl)-3-[2-(3-pyridyl)pyrimidin-4-yl]urea | MLS000706883 | N-(4-methylphenyl)-N'-[2-(3-pyridinyl)-4-pyrimidinyl]urea | SMR000335712 | cid_1477566
Type:
Small organic molecule
Emp. Form.:
C17H15N5O
Mol. Mass.:
305.3339
SMILES:
Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1
Structure:
Search PDB for entries with ligand similarity: