Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47686
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
637.7±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47686
Synonyms:
(4E)-2-methoxy-4-[[(6-methyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinyl)hydrazo]methylidene]-1-cyclohexa-2,5-dienone | (4E)-2-methoxy-4-[[2-(6-methyl-1-phenyl-pyrazolo[3,4-d]pyrimidin-4-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one | (4E)-2-methoxy-4-[[2-(6-methyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one | (4E)-2-methoxy-4-[[N'-(6-methyl-1-phenyl-pyrazolo[3,4-d]pyrimidin-4-yl)hydrazino]methylene]cyclohexa-2,5-dien-1-one | MLS000761535 | SMR000371629 | cid_5997241
Type:
Small organic molecule
Emp. Form.:
C20H18N6O2
Mol. Mass.:
374.3959
SMILES:
COc1cc(CN=Nc2nc(C)nc3n(ncc23)-c2ccccc2)ccc1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: