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Target
Regulator of G-protein signaling 8
Ligand
BDBM47741
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47741
Synonyms:
MLS000584249 | N'-[(1E)-(2-methoxyphenyl)methylene]-1,1'-biphenyl-4-carbohydrazide | N-(o-anisylideneamino)-4-phenyl-benzamide | N-[(2-methoxyphenyl)methylideneamino]-4-phenyl-benzamide | N-[(2-methoxyphenyl)methylideneamino]-4-phenylbenzamide | SMR000203412 | cid_768139
Type:
Small organic molecule
Emp. Form.:
C21H18N2O2
Mol. Mass.:
330.3798
SMILES:
COc1ccccc1C=NNC(=O)c1ccc(cc1)-c1ccccc1 |w:9.10|
Structure:
Search PDB for entries with ligand similarity: