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Target
Regulator of G-protein signaling 8
Ligand
BDBM47824
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47824
Synonyms:
(E)-3-(2-furanyl)-N-[(4-sulfamoylphenyl)methyl]-2-propenamide | (E)-3-(2-furyl)-N-(4-sulfamoylbenzyl)acrylamide | (E)-3-(furan-2-yl)-N-[(4-sulfamoylphenyl)methyl]prop-2-enamide | MLS000774310 | SMR000365355 | cid_2551912
Type:
Small organic molecule
Emp. Form.:
C14H14N2O4S
Mol. Mass.:
306.337
SMILES:
NS(=O)(=O)c1ccc(CNC(=O)\C=C\c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: