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Target
Regulator of G-protein signaling 7
Ligand
BDBM47769
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47769
Synonyms:
2-[4-(2,6-dimethyl-4-morpholinyl)butoxy]benzoic acid methyl ester;oxalic acid | 2-[4-(2,6-dimethylmorpholino)butoxy]benzoic acid methyl ester;oxalic acid | MLS000680797 | SMR000272513 | cid_2934198 | ethanedioic acid;methyl 2-[4-(2,6-dimethylmorpholin-4-yl)butoxy]benzoate | methyl 2-[4-(2,6-dimethyl-4-morpholinyl)butoxy]benzoate oxalate | methyl 2-[4-(2,6-dimethylmorpholin-4-yl)butoxy]benzoate;oxalic acid
Type:
Small organic molecule
Emp. Form.:
C18H27NO4
Mol. Mass.:
321.4113
SMILES:
COC(=O)c1ccccc1OCCCCN1CC(C)OC(C)C1
Structure:
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