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Target
Regulator of G-protein signaling 7
Ligand
BDBM47786
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47786
Synonyms:
6-chloro-3-pyridinecarboxylic acid [2-(tert-butylamino)-2-oxoethyl] ester | 6-chloronicotinic acid [2-(tert-butylamino)-2-keto-ethyl] ester | MLS000709523 | SMR000286890 | [2-(tert-butylamino)-2-oxidanylidene-ethyl] 6-chloranylpyridine-3-carboxylate | [2-(tert-butylamino)-2-oxoethyl] 6-chloropyridine-3-carboxylate | cid_2432404
Type:
Small organic molecule
Emp. Form.:
C12H15ClN2O3
Mol. Mass.:
270.712
SMILES:
CC(C)(C)NC(=O)COC(=O)c1ccc(Cl)nc1
Structure:
Search PDB for entries with ligand similarity: