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Target
Regulator of G-protein signaling 7
Ligand
BDBM47805
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47805
Synonyms:
3-amino-N-cyclopentyl-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxamide | 3-amino-N-cyclopentyl-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide | 3-amino-N-cyclopentyl-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide | 3-azanyl-N-cyclopentyl-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide | MLS001018026 | SMR000354275 | cid_2348592
Type:
Small organic molecule
Emp. Form.:
C15H19N3OS
Mol. Mass.:
289.396
SMILES:
Cc1cc(C)c2c(N)c(sc2n1)C(=O)NC1CCCC1
Structure:
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