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Target
Regulator of G-protein signaling 16
Ligand
BDBM40034
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM40034
Synonyms:
MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin-6-yl)-4-piperidino-piperidine-1-carboxamide | N-(4-methyl-3-oxidanylidene-1,4-benzothiazin-6-yl)-4-piperidin-1-yl-piperidine-1-carboxamide | N-(4-methyl-3-oxo-1,4-benzothiazin-6-yl)-4-(1-piperidinyl)-1-piperidinecarboxamide | N-(4-methyl-3-oxo-1,4-benzothiazin-6-yl)-4-piperidin-1-ylpiperidine-1-carboxamide | N-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)-1,4'-bipiperidine-1'-carboxamide | SMR000029191 | cid_3241667
Type:
Small organic molecule
Emp. Form.:
C20H28N4O2S
Mol. Mass.:
388.527
SMILES:
CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12
Structure:
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