Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 16
Ligand
BDBM47802
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47802
Synonyms:
2-thiophenecarboxylic acid [4-[4-(dimethoxymethyl)-2-pyrimidinyl]phenyl] ester | 4-[4-(dimethoxymethyl)-2-pyrimidinyl]phenyl 2-thiophenecarboxylate | MLS000721168 | SMR000335588 | [4-[4-(dimethoxymethyl)pyrimidin-2-yl]phenyl] thiophene-2-carboxylate | cid_1491140 | thiophene-2-carboxylic acid [4-[4-(dimethoxymethyl)pyrimidin-2-yl]phenyl] ester
Type:
Small organic molecule
Emp. Form.:
C18H16N2O4S
Mol. Mass.:
356.396
SMILES:
COC(OC)c1ccnc(n1)-c1ccc(OC(=O)c2cccs2)cc1
Structure:
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