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Target
Regulator of G-protein signaling 16
Ligand
BDBM47806
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47806
Synonyms:
6-amino-5-[1-oxo-2-[[4-oxo-3-(phenylmethyl)-2-quinazolinyl]thio]ethyl]-1-propylpyrimidine-2,4-dione | 6-amino-5-[2-(3-benzyl-4-oxoquinazolin-2-yl)sulfanylacetyl]-1-propylpyrimidine-2,4-dione | 6-amino-5-[2-[(3-benzyl-4-keto-quinazolin-2-yl)thio]acetyl]-1-propyl-pyrimidine-2,4-quinone | 6-azanyl-5-[2-[4-oxidanylidene-3-(phenylmethyl)quinazolin-2-yl]sulfanylethanoyl]-1-propyl-pyrimidine-2,4-dione | MLS001004090 | SMR000377686 | cid_2566659
Type:
Small organic molecule
Emp. Form.:
C24H23N5O4S
Mol. Mass.:
477.536
SMILES:
CCCn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)[nH]c1=O
Structure:
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