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Target
3C-like protease
Ligand
BDBM47838
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
6310±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47838
Synonyms:
4-chlorobenzoic acid 3-pyridinyl ester;hydrochloride | 4-chlorobenzoic acid 3-pyridyl ester;hydrochloride | MLS000036206 | SMR000035693 | cid_6602830 | pyridin-3-yl 4-chloranylbenzoate;hydrochloride | pyridin-3-yl 4-chlorobenzoate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C12H8ClNO2
Mol. Mass.:
233.65
SMILES:
Clc1ccc(cc1)C(=O)Oc1cccnc1
Structure:
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