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Target
3C-like protease
Ligand
BDBM37254
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
10447±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM37254
Synonyms:
10-phenothiazinecarbothioic acid S-(5-methyl-1,3,4-thiadiazol-2-yl) ester | MLS000112617 | S-(5-methyl-1,3,4-thiadiazol-2-yl) phenothiazine-10-carbothioate | SMR000108529 | cid_1160939 | phenothiazine-10-carbothioic acid S-(5-methyl-1,3,4-thiadiazol-2-yl) ester
Type:
Small organic molecule
Emp. Form.:
C16H11N3OS3
Mol. Mass.:
357.473
SMILES:
Cc1nnc(SC(=O)N2c3ccccc3Sc3ccccc23)s1
Structure:
Search PDB for entries with ligand similarity: