Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46182
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies
IC50
14700±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46182
Synonyms:
MLS-0202046.0001 | N-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-phenyl-1-pyrrolidinecarboxamide | N-[2,3-bis(2-furyl)quinoxalin-6-yl]-3-phenyl-pyrrolidine-1-carboxamide | N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-phenyl-pyrrolidine-1-carboxamide | N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-phenylpyrrolidine-1-carboxamide | cid_2925154
Type:
Small organic molecule
Emp. Form.:
C27H22N4O3
Mol. Mass.:
450.4886
SMILES:
O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCC(C1)c1ccccc1
Structure:
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