Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46284
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46284
Synonyms:
(4E)-4-[[(4-chloranyl-3-methyl-phenyl)methylamino]-sulfanyl-methylidene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[(4-chloro-3-methyl-benzyl)amino]-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[(4-chloro-3-methylphenyl)methylamino]-mercaptomethylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[[(4-chloro-3-methylphenyl)methylamino]-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | MLS-0425621.0001 | cid_44229070
Type:
Small organic molecule
Emp. Form.:
C16H16ClNO2S
Mol. Mass.:
321.822
SMILES:
COc1cc(ccc1O)C(=S)NCc1ccc(Cl)c(C)c1
Structure:
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