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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48212
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
270±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48212
Synonyms:
3-(4-Methoxy-phenyl)-7-piperidin-1-yl-isothiazolo[4,5-d]pyrimidine | 3-(4-methoxyphenyl)-7-(1-piperidinyl)isothiazolo[4,5-d]pyrimidine | 3-(4-methoxyphenyl)-7-piperidin-1-yl-[1,2]thiazolo[4,5-d]pyrimidine | 3-(4-methoxyphenyl)-7-piperidino-isothiazolo[4,5-d]pyrimidine | MLS000067913 | SMR000122451 | cid_1462058
Type:
Small organic molecule
Emp. Form.:
C17H18N4OS
Mol. Mass.:
326.416
SMILES:
COc1ccc(cc1)-c1nsc2c(ncnc12)N1CCCCC1
Structure:
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