Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48289
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
590±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48289
Synonyms:
2-(1H-benzimidazol-2-yl)-4-chloranyl-5-piperidin-1-yl-pyridazin-3-one | 2-(1H-benzimidazol-2-yl)-4-chloro-5-(1-piperidinyl)-3-pyridazinone | 2-(1H-benzimidazol-2-yl)-4-chloro-5-piperidin-1-ylpyridazin-3-one | 2-(1H-benzimidazol-2-yl)-4-chloro-5-piperidino-pyridazin-3-one | MLS000564138 | SMR000151679 | cid_2386027
Type:
Small organic molecule
Emp. Form.:
C16H16ClN5O
Mol. Mass.:
329.784
SMILES:
Clc1c(cnn(-c2nc3ccccc3[nH]2)c1=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: