Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48903
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00407±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48903
Synonyms:
2-(6-indolo[3,2-b]quinoxalinyl)acetic acid ethyl ester | 2-indolo[3,2-b]quinoxalin-6-ylacetic acid ethyl ester | Indolo[2,3-b]quinoxalin-6-yl-acetic acid ethyl ester | MLS000035955 | SMR000001010 | cid_645300 | ethyl 2-indolo[3,2-b]quinoxalin-6-ylacetate | ethyl 2-indolo[3,2-b]quinoxalin-6-ylethanoate
Type:
Small organic molecule
Emp. Form.:
C18H15N3O2
Mol. Mass.:
305.3306
SMILES:
CCOC(=O)Cn1c2ccccc2c2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: