Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48940
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00817±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48940
Synonyms:
(4-oxidanylidene-1,2,3-benzotriazin-3-yl)methyl 1-thiophen-2-ylsulfonylpiperidine-4-carboxylate | (4-oxo-1,2,3-benzotriazin-3-yl)methyl 1-thiophen-2-ylsulfonylpiperidine-4-carboxylate | 1-(2-thienylsulfonyl)isonipecotic acid (4-keto-1,2,3-benzotriazin-3-yl)methyl ester | 1-thiophen-2-ylsulfonyl-4-piperidinecarboxylic acid (4-oxo-1,2,3-benzotriazin-3-yl)methyl ester | MLS000053510 | SMR000063603 | cid_2121421
Type:
Small organic molecule
Emp. Form.:
C18H18N4O5S2
Mol. Mass.:
434.489
SMILES:
O=C(OCn1nnc2ccccc2c1=O)C1CCN(CC1)S(=O)(=O)c1cccs1
Structure:
Search PDB for entries with ligand similarity: