Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48957
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00103±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48957
Synonyms:
(5Z)-2-(1-azepanyl)-5-(7-bromo-5-methyl-2-oxo-1H-indol-3-ylidene)-4-thiazolone | (5Z)-2-(azepan-1-yl)-5-(7-bromanyl-5-methyl-2-oxidanylidene-1H-indol-3-ylidene)-1,3-thiazol-4-one | (5Z)-2-(azepan-1-yl)-5-(7-bromo-2-keto-5-methyl-indolin-3-ylidene)-2-thiazolin-4-one | (5Z)-2-(azepan-1-yl)-5-(7-bromo-5-methyl-2-oxo-1H-indol-3-ylidene)-1,3-thiazol-4-one | 3-[2-(1-azepanyl)-4-oxo-1,3-thiazol-5(4H)-ylidene]-7-bromo-5-methyl-1,3-dihydro-2H-indol-2-one | MLS000050455 | SMR000076359 | cid_5739634
Type:
Small organic molecule
Emp. Form.:
C18H18BrN3O2S
Mol. Mass.:
420.323
SMILES:
Cc1cc2\C(C(=O)Nc2c(Br)c1)=C1\SC(=NC1=O)N1CCCCCC1 |c:16|
Structure:
Search PDB for entries with ligand similarity: