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Target
D(1A) dopamine receptor
Ligand
BDBM48915
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00918±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM48915
Synonyms:
4-(4-Methylamino-6-methylsulfanyl-[1,3,5]triazin-2-yloxy)-benzoic acid ethyl ester | 4-[[4-(methylamino)-6-(methylthio)-1,3,5-triazin-2-yl]oxy]benzoic acid ethyl ester | 4-[[4-(methylamino)-6-(methylthio)-s-triazin-2-yl]oxy]benzoic acid ethyl ester | MLS000070171 | SMR000011044 | cid_654452 | ethyl 4-[[4-(methylamino)-6-methylsulfanyl-1,3,5-triazin-2-yl]oxy]benzoate
Type:
Small organic molecule
Emp. Form.:
C14H16N4O3S
Mol. Mass.:
320.367
SMILES:
CCOC(=O)c1ccc(Oc2nc(NC)nc(SC)n2)cc1
Structure:
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