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Target
D(1A) dopamine receptor
Ligand
BDBM49039
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00366±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49039
Synonyms:
MLS000098496 | N-[5-chloranyl-2-(4-methylpiperazin-1-yl)phenyl]-3-(dimethylsulfamoyl)benzamide | N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamide | N-[5-chloro-2-(4-methylpiperazin-1-yl)phenyl]-3-(dimethylsulfamoyl)benzamide | N-[5-chloro-2-(4-methylpiperazino)phenyl]-3-(dimethylsulfamoyl)benzamide | SMR000065446 | cid_2670170
Type:
Small organic molecule
Emp. Form.:
C20H25ClN4O3S
Mol. Mass.:
436.956
SMILES:
CN(C)S(=O)(=O)c1cccc(c1)C(=O)Nc1cc(Cl)ccc1N1CCN(C)CC1
Structure:
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