Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM49051
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00279±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49051
Synonyms:
1-[1-(3-chlorophenyl)-4-(2-furoyl)-1H-pyrazol-3-yl]ethanone | 1-[1-(3-chlorophenyl)-4-(2-furoyl)pyrazol-3-yl]ethanone | 1-[1-(3-chlorophenyl)-4-(furan-2-carbonyl)pyrazol-3-yl]ethanone | 1-[1-(3-chlorophenyl)-4-(furan-2-ylcarbonyl)pyrazol-3-yl]ethanone | 1-[1-(3-chlorophenyl)-4-[2-furanyl(oxo)methyl]-3-pyrazolyl]ethanone | MLS000043778 | SMR000020988 | cid_565311
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O3
Mol. Mass.:
314.723
SMILES:
CC(=O)c1nn(cc1C(=O)c1ccco1)-c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: