Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM49128
Substrate
n/a
Meas. Tech.
Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay
IC50
23±n/a nM
Citation
 PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM49128
Synonyms:
4-[2-(2-chloranyl-4-morpholin-4-ylsulfonyl-phenoxy)ethanoyl]-3,3-dimethyl-1H-quinoxalin-2-one | 4-[2-(2-chloro-4-morpholin-4-ylsulfonylphenoxy)acetyl]-3,3-dimethyl-1H-quinoxalin-2-one | 4-[2-(2-chloro-4-morpholinosulfonyl-phenoxy)acetyl]-3,3-dimethyl-1H-quinoxalin-2-one | 4-[2-[2-chloro-4-(4-morpholinylsulfonyl)phenoxy]-1-oxoethyl]-3,3-dimethyl-1H-quinoxalin-2-one | MLS000058675 | SMR000066903 | cid_2115719
Type:
Small organic molecule
Emp. Form.:
C22H24ClN3O6S
Mol. Mass.:
493.96
SMILES:
CC1(C)N(C(=O)COc2ccc(cc2Cl)S(=O)(=O)N2CCOCC2)c2ccccc2NC1=O
Structure:
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