Reaction Details Report a problem with these data
Target
Transcription factor p65
Ligand
BDBM43824
Substrate
n/a
Meas. Tech.
Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50
762±n/a nM
Citation
 PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay (2008)[AID] 
Target
Name:
Transcription factor p65
Synonyms:
NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:
Enzyme
Mol. Mass.:
60211.92
Organism:
Homo sapiens (Human)
Description:
Q04206
Residue:
551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
  
Inhibitor
Name:
BDBM43824
Synonyms:
Aminoglycosides, 2 | MLS000533892 | N-[(E)-N''''-(1,3-benzothiazol-2-yl)amidino]-3-methyl-butyramide | N-[(E)-N''''-(1,3-benzothiazol-2-yl)carbamimidoyl]-3-methyl-butanamide | N-[(E)-N''''-(1,3-benzothiazol-2-yl)carbamimidoyl]-3-methylbutanamide | N-[(E)-N''-(1,3-benzothiazol-2-yl)amidino]-3-methyl-butyramide | N-[(E)-N'-(1,3-benzothiazol-2-yl)amidino]-3-methyl-butyramide | N-[(E)-amino(1,3-benzothiazol-2-ylimino)methyl]-3-methylbutanamide | N-[amino(1,3-benzothiazol-2-ylamino)methylene]-3-methylbutanamide | SMR000141329 | cid_9551574
Type:
Small organic molecule
Emp. Form.:
C13H16N4OS
Mol. Mass.:
276.357
SMILES:
CC(C)CC(=O)NC(N)=Nc1nc2ccccc2s1 |w:9.9|
Structure:
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