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Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM39401
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM39401
Synonyms:
4-[4-(4-methoxyphenyl)piperazin-1-yl]carbonyl-2,9-dimethyl-pyrido[3,4-b]indol-1-one | 4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-2,9-dimethyl-beta-carbolin-1-one | 4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-2,9-dimethylpyrido[3,4-b]indol-1-one | 4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]-2,9-dimethyl-1-pyrido[3,4-b]indolone | 4-{[4-(4-methoxyphenyl)piperazin-1-yl]carbonyl}-2,9-dimethyl-2,9-dihydro-1H-beta-carbolin-1-one | MLS000086987 | SMR000023210 | cid_3243804
Type:
Small organic molecule
Emp. Form.:
C25H26N4O3
Mol. Mass.:
430.4989
SMILES:
COc1ccc(cc1)N1CCN(CC1)C(=O)c1cn(C)c(=O)c2n(C)c3ccccc3c12
Structure:
Search PDB for entries with ligand similarity: