Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51326
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51326
Synonyms:
1-(3,5-dimethylphenyl)-3-(1-phenyltetrazol-5-yl)sulfanylpyrrolidine-2,5-dione | 1-(3,5-dimethylphenyl)-3-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione | 1-(3,5-dimethylphenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)thio]-2,5-pyrrolidinedione | 1-(3,5-dimethylphenyl)-3-[(1-phenyl-5-tetrazolyl)thio]pyrrolidine-2,5-dione | 1-(3,5-dimethylphenyl)-3-[(1-phenyltetrazol-5-yl)thio]pyrrolidine-2,5-quinone | MLS000576813 | SMR000198093 | cid_2936558
Type:
Small organic molecule
Emp. Form.:
C19H17N5O2S
Mol. Mass.:
379.436
SMILES:
Cc1cc(C)cc(c1)-n1c(O)cc(Sc2nnnn2-c2ccccc2)c1O
Structure:
Search PDB for entries with ligand similarity: