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Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51361
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51361
Synonyms:
MLS000721625 | SMR000335930 | [4-(2,4-dimethylphenyl)piperazino][4-(2-methylbenzoyl)-1H-pyrrol-2-yl]methanone | [5-[4-(2,4-dimethylphenyl)piperazin-1-yl]carbonyl-1H-pyrrol-3-yl]-(2-methylphenyl)methanone | [5-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]-1H-pyrrol-3-yl]-(2-methylphenyl)methanone | [5-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]-1H-pyrrol-3-yl]-(o-tolyl)methanone | [5-[[4-(2,4-dimethylphenyl)-1-piperazinyl]-oxomethyl]-1H-pyrrol-3-yl]-(2-methylphenyl)methanone | cid_1489222
Type:
Small organic molecule
Emp. Form.:
C25H27N3O2
Mol. Mass.:
401.5008
SMILES:
Cc1ccc(N2CCN(CC2)C(=O)c2cc(c[nH]2)C(=O)c2ccccc2C)c(C)c1
Structure:
Search PDB for entries with ligand similarity: