Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51503
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
555±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51503
Synonyms:
2-[8-(diethylaminomethyl)-7-hydroxy-2-keto-4-methyl-chromen-3-yl]acetic acid methyl ester;hydrochloride | 2-[8-(diethylaminomethyl)-7-hydroxy-4-methyl-2-oxo-1-benzopyran-3-yl]acetic acid methyl ester;hydrochloride | MLS000081528 | SMR000043423 | cid_6603244 | methyl 2-[8-(diethylaminomethyl)-4-methyl-7-oxidanyl-2-oxidanylidene-chromen-3-yl]ethanoate;hydrochloride | methyl 2-[8-(diethylaminomethyl)-7-hydroxy-4-methyl-2-oxochromen-3-yl]acetate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C18H23NO5
Mol. Mass.:
333.3789
SMILES:
CCN(CC)Cc1c(O)ccc2c(C)c(CC(=O)OC)c(=O)oc12
Structure:
Search PDB for entries with ligand similarity: