Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51673
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
606±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51673
Synonyms:
2-[7-hydroxy-2-keto-4-methyl-8-[(3-methylpiperidino)methyl]chromen-3-yl]acetic acid methyl ester | 2-[7-hydroxy-4-methyl-8-[(3-methyl-1-piperidinyl)methyl]-2-oxo-1-benzopyran-3-yl]acetic acid methyl ester | MLS000551543 | SMR000145468 | [7-Hydroxy-4-methyl-8-(3-methyl-piperidin-1-ylmethyl)-2-oxo-2H-chromen-3-yl]-acetic acid methyl ester | cid_5892724 | methyl 2-[4-methyl-8-[(3-methylpiperidin-1-yl)methyl]-7-oxidanyl-2-oxidanylidene-chromen-3-yl]ethanoate | methyl 2-[7-hydroxy-4-methyl-8-[(3-methylpiperidin-1-yl)methyl]-2-oxochromen-3-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C20H25NO5
Mol. Mass.:
359.4162
SMILES:
COC(=O)Cc1c(C)c2ccc(O)c(CN3CCCC(C)C3)c2oc1=O
Structure:
Search PDB for entries with ligand similarity: