Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47712
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47712
Synonyms:
4-bromanyl-2-[[(1-methylbenzimidazol-2-yl)amino]methyl]phenol | 4-bromo-2-[[(1-methyl-2-benzimidazolyl)amino]methyl]phenol | 4-bromo-2-[[(1-methylbenzimidazol-2-yl)amino]methyl]phenol | MLS000110519 | SMR000106448 | cid_715151
Type:
Small organic molecule
Emp. Form.:
C15H14BrN3O
Mol. Mass.:
332.195
SMILES:
Cn1c(NCc2cc(Br)ccc2O)nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: