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Target
Regulator of G-protein signaling 4
Ligand
BDBM47761
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47761
Synonyms:
2-(5-nitropyridin-2-yl)sulfanylpyridin-3-amine | 2-[(5-nitro-2-pyridinyl)thio]-3-pyridinamine | 3-amino-2-({5-nitropyridin-2-yl}thio)pyridine | MLS000702477 | SMR000226877 | [2-[(5-nitro-2-pyridyl)thio]-3-pyridyl]amine | cid_901969
Type:
Small organic molecule
Emp. Form.:
C10H8N4O2S
Mol. Mass.:
248.261
SMILES:
Nc1cccnc1Sc1ccc(cn1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: