Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47816
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
3080±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47816
Synonyms:
6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid (3-methoxy-propyl)-amide | MLS001029502 | SMR000425486 | cid_3729555
Type:
Small organic molecule
Emp. Form.:
C19H16N2O4
Mol. Mass.:
336.3413
SMILES:
COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23
Structure:
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