Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47822
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47822
Synonyms:
3-[5-(2-furanyl)-1H-pyrazol-3-yl]-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | 3-[5-(2-furyl)-1H-pyrazol-3-yl]-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | 3-[5-(furan-2-yl)-1H-pyrazol-3-yl]-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | 5-(5-Furan-2-yl-2H-pyrazol-3-yl)-4-(2-methoxy-phenyl)-4H-[1,2,4]triazole-3-thiol | MLS000769411 | SMR000434141 | cid_950682
Type:
Small organic molecule
Emp. Form.:
C16H13N5O2S
Mol. Mass.:
339.372
SMILES:
COc1ccccc1-n1c(n[nH]c1=S)-c1cc([nH]n1)-c1ccco1 |(3.08,-1.56,;4.41,-.79,;5.75,-1.56,;5.75,-3.1,;7.08,-3.87,;8.41,-3.1,;8.41,-1.56,;7.08,-.79,;7.08,.75,;8.33,1.66,;7.85,3.12,;6.31,3.12,;5.84,1.66,;4.37,1.18,;9.79,1.18,;10.27,-.28,;11.81,-.28,;12.28,1.18,;11.04,2.09,;12.71,-1.53,;14.25,-1.53,;14.73,-2.99,;13.48,-3.9,;12.24,-2.99,)|
Structure:
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