Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47831
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47831
Synonyms:
MLS001111288 | N-[4-(4-fluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-2-furamide | N-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)-3-pyrazolyl]-2-furancarboxamide | N-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-2-furamide | N-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]furan-2-carboxamide | SMR000458048 | cid_2809607
Type:
Small organic molecule
Emp. Form.:
C16H11F4N3O2
Mol. Mass.:
353.2711
SMILES:
Cn1nc(c(c1NC(=O)c1ccco1)-c1ccc(F)cc1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: