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Target
Beta-lactamase
Ligand
BDBM51979
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
34102±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51979
Synonyms:
3-(4-tert-butylphenyl)-4-(3-morpholin-4-ylpropyl)-1H-1,2,4-triazole-5-thione | 3-(4-tert-butylphenyl)-4-(3-morpholinopropyl)-1H-1,2,4-triazole-5-thione | 3-(4-tert-butylphenyl)-4-[3-(4-morpholinyl)propyl]-1H-1,2,4-triazole-5-thione | 5-(4-tert-butylphenyl)-4-[3-(4-morpholinyl)propyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000666451 | SMR000294279 | cid_2208886
Type:
Small organic molecule
Emp. Form.:
C19H28N4OS
Mol. Mass.:
360.517
SMILES:
CC(C)(C)c1ccc(cc1)-c1n[nH]c(=S)n1CCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: