Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM52008
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
373.61±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM52008
Synonyms:
3-[2-[1,3-bis(oxidanylidene)isoindol-2-yl]ethyl]-5-chloranyl-1H-indole-2-carboxylic acid | 5-Chloro-3-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-1H-indole-2-carboxylic acid | 5-chloro-3-(2-phthalimidoethyl)-1H-indole-2-carboxylic acid | 5-chloro-3-[2-(1,3-dioxo-2-isoindolyl)ethyl]-1H-indole-2-carboxylic acid | 5-chloro-3-[2-(1,3-dioxoisoindol-2-yl)ethyl]-1H-indole-2-carboxylic acid | MLS000778186 | SMR000414879 | cid_1547995
Type:
Small organic molecule
Emp. Form.:
C19H13ClN2O4
Mol. Mass.:
368.771
SMILES:
OC(=O)c1[nH]c2ccc(Cl)cc2c1CCN1C(=O)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: